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London School of Hygiene & Tropical Medicine Malaria Centre

Malaria research in drug development, deployment and resistance

Drug resistance maps to guide intermittent preventive treatment of malaria in African infants.

LSHTM investigators:
Cally Roper & Inbarani Naidoo.
Funding body:
The Bill & Melinda Gates foundation through the Gates Malaria Partnership and IPTi Consortium.

The data is available as a publically available web-based resource.

We have created a geographical database of the prevalence of point mutations in the dhfr and dhps genes of Plasmodium falciparum that confer resistance to sulphadoxine and pyrimethamine. This was used to guide WHO policy recommendations on SP-IPTi.