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London School of Hygiene & Tropical Medicine Malaria Centre

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Image: Patient undergoing test for malaria. Picture courtesy of Paul Milligan
 

Image: Patient undergoing test for malaria. Picture courtesy of Paul Milligan

18 November 2013
Piecing Together the Puzzle of Severe Malaria

Piecing Together the Puzzle of Severe Malaria

Aubrey J. Cunnington, Michael Walther, Eleanor M. Riley

Abstract

Severe malaria manifests as several overlapping syndromes with high mortality. Interaction of parasites with endothelial protein C receptors and high parasite biomass have recently been identified as key determinants of severe disease. However, gaps in our understanding of severe malaria might hinder translation of these findings into new therapies.

Read the full article in Science Translational Medicine.