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London School of Hygiene & Tropical Medicine Malaria Centre

Seminar | Surveillance approaches to detect the quality of medicines in low-middle income countries with a focus on ACTs

Tuesday 5 June 2018, 12:30 pm
John Snow B, Keppel Street
Malaria Centre Seminar


Recent years have seen an increase in reports of poor quality antimalarials with estimates that up to 30% have failed chemical analysis, even though robust empirical evidence for their prevalence remains scarce. Several risk factors may contribute to the circulation of poor quality medicines. This seminar will explore some of these factors, providing evidence to strengthen medicines quality surveillance systems (MQSS) in low-middle income countries (LMICs).

The seminar presents a series of findings studies undertaken in Senegal between March 2013 and April 2014. The studies explored the various components of a MQSS as well as perceptions of the quality of medicines available in Senegal.

Findings suggest a major shift is required in the framing of medicine quality from a technical/legal to a clinical paradigm with evidence required to demonstrate the impact of poor quality medicines on public health. National governments need to invest in regulatory and technical capacity to strengthen MQSS to minimise the likelihood of poor quality medicines circulating in a country. Utilising simple, and portable (preferably handheld) tests, in non-laboratory settings may enhance post-marketing surveillance, especially in resource constrained contexts. Suggestions for reducing the risk of bias and error in medicine quality studies to enable standardisation of study design and reporting are also provided.


Speaker: Mirza Lalani
Date: 5 June 2018
Time: 12:30 - 2:00 pm
Venue: John Snow B, Keppel Street