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London School of Hygiene & Tropical Medicine Malaria Centre

Seminar | Dissecting the CD8+ T cell responses to malaria pre-erythrocytic antigens

Wednesday 20 June 2018, 12:30
Bradford Hill LG8, Keppel Street
Immunology & Infection Seminar

Summary

The pre-erythrocytic stages of malaria are an attractive target for malaria vaccines because killing of the parasite in these stages would ultimately prevent malaria pathogenesis induced by the subsequent blood stage parasites. CD8+ T cells induced by antigens from the pre-erythrocytic stages are known to play a key role in mediating protection from malaria however the antigens that effectively induce this protection are largely unknown.

Here I will present research investigating the types of pre-erythrocytic antigens that induce protective CD8+ T cell responses as well as novel CD8+ T cell epitopes that we have discovered.

Details

Speaker: Matthew Gibbins 

Date: 20 June 2018 

Time: 12:30

Venue: LG8, Bradford Hill, Keppel Street