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London School of Hygiene & Tropical Medicine Malaria Centre

Malaria Centre Repository

 
 

Background

There have been many studies conducted under the auspices of the School, cross-sectional, longitudinal as well as intervention studies, which provide a valuable resource for future research both with respect to samples and data. The types of samples available differ between studies, but include serum samples, DNA and blood spots. The Malaria Centre has as one of its objectives, the setting up of a Malaria Repository to enable these resources to be organised and integrated to facilitate their use in future.

The aim of the repository is to provide a designated place for the storage of such samples, with a systematic labelling system which links each sample to a database providing baseline demographic and clinical information on the subject. This set up will facilitate the ability to search for appropriate samples that can then be made available for novel research.

Deposition of samples into the Malaria Repository

During the process of depositing samples such as sera and DNA into the repository, each sample is divided to create an archive sample and up to four aliquots which are stored in uniquely barcoded tubes, the location of which is been recorded in the master database. The samples themselves are stored in -80ÂșC freezers, in a secure long-term storage facility in the basement of Keppel Street, using a racking system which provides easy access to the samples. Archive and aliquot samples are stored separately in case of any unforeseen problem with the storage arrangements.

The repository currently contains a number of sample sets from West Africa, dating from the 1960s, up to the late 1990s.  For information about submitting a sample set, complete with relevant demographic data and ethical approval, please contact us.

Additionally, for information about samples currently held in the repository, and how to gain access to them, please contact us. Since these samples are unique and finite, it is important to ensure that these specimens are only utilised for research of the highest quality. To this end, guidelines have been drawn up for those interested in using repository samples in their research, and all requests for access to materials maintained in the specimen repositories will require a formal application which will be assessed by the Repository Advisory Committee.

 

Please direct all queries relating to the Malaria Centre Repository to rebecca [dot] dabbs [at] lshtm [dot] ac [dot] uk (Rebecca Dabbs).